Related Clues:

• On open waters
• On a 42-Across
• Gave the slip
• Out of harbor
• Dazed and confused
• Under sail
• A-mazed?
• On the Indian, e.g.
• Completely off-track
• See 9-Across
• Floating, perhaps
• In the main?
• Like the Titanic, before the iceberg
• On a cruise
• Like Santiago during most of the novel