Possible Clues:

• Movie with the line 'Old age. It's the only disease, Mr. Thompson, that you don't look forward to being cured of'
• Film in which Agnes Moorehead debuted as the title character's mother
• The New York Inquirer was featured in it
• AFI's top film
• Regarded by many as 'The best film of all time'
• Film society member at thrash for audience