Related Clues:

• Angry - furious
• Causing discomfort
• A tier (anag)
• Quite hot
• Needing some rubbing
• Acting up, in a way
• Totally ticked off
• Like overused muscles
• In a steamed state
• Hook loses head with anger
• Seeing red paramilitary group looking back for alien
• Sore, and more
• Having throbbing temples, maybe
• Plenty upset
• Regretting yesterday's activity, perhaps