Related Clues:

• Cause of grief
• Deep sorrow
• Grievous distress
• ''__ is me!''
• Deep sadness
• Remorseful feeling
• Tragedy
• "___ is me!"
• Cause of trouble
• With 51-Down, cry of sorrow
• Job's lot?
• Great sorrow
• What a lift may get you out of
• What any of the Four Horsemen symbolizes
• "___ is me!" ("Alas!")