Related Clues:

• Anguish
• Doomsayer's cry
• Ills
• Tsuris, so to speak
• Unhappiness
• Heartbreak
• Adversity
• "Alas!"
• Gloomy state
• Begone beginning
• Unfortunate condition
• The 'vey' of 'oy vey!'
• Topic of some tales
• Reason to say 'alas'
• Handwringer's feeling