Related Clues:

• Be a nuisance to
• Be a pain to
• Get quite hot
• Do some button-pushing, so to speak
• Bring to the boiling point
• Make very mad
• Send off the deep end
• Fester in one's mind
• Continue to irritate
• Bother big-time
• Make livid
• Be a pest
• Test the patience of
• Make one's blood boil
• Make boiling mad