Related Clues:

• Cause disquiet
• Be a noodge to
• Be a thorn in the side of
• Bother greatly
• Bug the hell out of
• Rile or rankle
• Be a nuisance to
• Eat at
• Be a pain to
• Be a royal pain to
• Do some button-pushing, so to speak
• Irk like crazy
• Be a pest
• Keep poking, perhaps
• Test the patience of