Possible Clues:

• Dutch city, home to St. Martin's Cathedral
• It's northeast of Rotterdam
• The curt drunk in foreign city
• Dutch city known for its university
• The curt Yank from Dutch city
• The curt upheaval here in the Netherlands
• Netherlands province
• Unreal train route leads to genuine province
• Dutch city whose name was given to a 1713 treaty
• City of central Holland