Possible Clues:

• 100-eyed guardian of myth
• Out of bounds, large American giant
• 100-eyed mythical giant
• Debates lacking energy in the Guardian
• ___ Paige Johnson, co-creator of TV's 'Blue's Clues'
• Mythical 100-eyed guardian
• Hundred-eyed giant of Greek myth
• In Greek mythology, a giant with a hundred eyes
• Guardian's refined sugar
• Lookout is in disagreement with ecstasy being taken