Related Clues:

• Make upset
• Get on one's nerves
• Piss off
• Raise one's hackles
• Try the patience of
• Get on the bad side of
• Cause disquiet
• Be a thorn in the side of
• Bother greatly
• Bug the hell out of
• Be a nuisance to
• Eat at
• Be a pain to
• Do some button-pushing, so to speak
• Be a pest