Related Clues:

• Impairs
• Lops an arm off of, say
• Kneecaps, e.g.
• Makes defective
• Really hurts
• Severely injures
• Seriously harms
• Seriously injures
• But, monsieur, in French it means 'mutilates'
• Injures grievously
• Injures severely, in a way
• Seriously hurts
• Badly injures
• Impairs severely
• Disfigures, say