Related Clues:

• Needle, perhaps
• Boil one's blood
• Really annoy
• Passage
• Bring exasperation
• Chafe
• Bother the heck out of
• Gnaw at
• Make hot
• Incite anger in
• Really ruffle
• Outsiders may not get it
• Cause one to get het up
• Arouse resentment
• Be a pest to