Related Clues:

• Used to go out with to hotel for drink to get something off one's chest
• Let air out
• Pressure after vote in nearby country's become invalid
• Nurse's vocation - no end of trouble
• Get out of breath
• Cease to be valid
• Puff, perhaps, previously fit
• Lapse; die
• Die as tide comes up in river
• No longer healthy? Be a puffer maybe
• One attending invalid
• Responsible person's occupation out East
• One tending to be short of energy in a rush
• Invalid's attendant
• One looking after invalid