Related Clues:

• Bratty kid
• Minor but aggravating problem
• Aspirin's target
• Reliever's target
• Pain in the behind
• Baby brother, often
• Annoyance, so to speak
• Badger or hound
• Partner of suffering
• Be a pain in the neck
• Result of punishment
• Pill
• Grimace inducer
• Major hassle
• 'No ___, no gain'