Related Clues:

• Culmination's opposite
• It's as low as you can go
• Bottommost point
• Anagram for "drain"
• Most hopeless moment
• The very bottom
• All-time low
• Acme's opposite
• The lowest point to drain into
• Point opposite the zenith
• The lowest point
• Lowest point, or time of deepest depression.
• Catastrophe, calamity
• Drain to lowest level
• Event resulting in great loss and misfortune