Related Clues:

• Brief pain spasm
• 'The poison of life,' per Brontë's Rochester
• Put to ___ (outdo)
• Sudden ache
• Ache of a sort
• Indication of hunger
• "Fool me once, ___ . . .
• Sharp twinge of pain
• Feeling of regret for wrongdoing
• Pain of conscience
• Sharp pain, of hunger or emotion perhaps
• A small pang, of pain or concience
• Gnawing pain of conscience
• Distress from a sense of guilt
• Sorrow for wrongs committed