Related Clues:

• Makes cloudy
• Is abrasive
• Bugs big-time
• The Wire's neighbours have no heroin
• Steamed states
• Ruffles the feathers of
• Gets one's 53-Down
• Irritates incessantly
• Deeply disturbs
• Program errors
• Narks
• Pet problems?
• Worries to no end
• Puts out of sorts
• Conniving carrot cruncher