Related Clues:
- Pain of a sort
- Pain in the rear
- Mixed-up PETS?
- Orkin victim
- Kibitzer, e.g.
- Gnat, for one
- Kid brother, stereotypically
- Major inconvenience
- Unwelcome greenhouse guest
- Bugging bug
- With 65-Across, extermination ... or what can be done to 10 answers in this puzzle without affecting their clues?
- Cockroach or termite
- Vexatious one
- Irksome type
- Mosquito or fly