Related Clues:

• Genuine nuisance
• Telemarketer, perhaps
• Brat or bug, e.g.
• Gnat or brat
• Mole, to a gardener
• Vexatious problem
• Mite, moth or mole
• Pain in the brain
• Raid victim
• Pain, so to speak
• Pain in the you-know-what, e.g.
• ___ control
• Slug, say
• Bothersome insect
• Fumigation target