Related Clues:

• Cause of a blowup
• Drive bananas
• Miffed
• Pique experience
• Deadly sin
• Get under one's skin
• Burning feeling
• Wexford's locale: Abbr.
• Exasperate
• Beside oneself
• For some, it's a burning sensation
• In turmoil
• Really bother
• Steam
• 'It could not slake mine ___, nor ease my heart': Shak.