Related Clues:
- Tangled threads most difficult to unravel
- Spinning threads can be most difficult
- Disentangling threads is most difficult
- Red hats (anag.)
- Most domineering
- Firmest
- The ultimate in knots
- Badly trashed, like last clue solved?
- Most difficult dart he's thrown
- Trashed (anag) — most oppressive
- Doctor rising in haste dressed with extreme energy
- Unravelling threads is most difficult
- Most domineering and overbearing
- Most arduous
- Most challenging