Related Clues:

• Existential suffering
• Cabin fever, e.g.
• Extreme apprehension
• Emotional strife
• Woody Allen has it
• Inner turmoil
• Be apprehensive
• Major apprehension
• Existential discomfort
• Neurotic feeling
• Fear facing
• Acute but unspecific anxiety
• More than misgivings
• See 56 Down
• Anxiety variety