Related Clues:
- New York's most populous upstate county
- Iroquois foes
- Lake near Niagara Falls
- Eastern Woodlands tribe
- New York tribe
- Lake ___ College, in 16-Across
- Sandusky's county
- One of a great quintet
- The shallowest Great Lake
- Indians with poisoned arrows
- Great Lakes tribesmen
- Early Iroquois foes
- ___-Lackawanna Railroad
- Strange-sounding city?
- Home to Commodore Perry's ship Niagara