Related Clues:

• Kerouac or Burroughs
• It may be taken by a 46-Across
• Ready to hit the hay
• Out of gas
• About ready to drop
• Apt rhyme for defeat
• Bested
• Heartbeat
• Paramedics search for it
• Conductor's concern
• Rhythm
• Sign of life
• All in
• Heart throbs
• Blender button