Related Clues:

• Irked
• All --- up (agitated)
• Angry, with 'up'
• Steamed up
• Beside oneself
• -- up (excited)
• Rubbed the wrong way
• Badly agitated, with 'up'
• Got under the skin of
• Made angry
• Plenty ticked, with 'up'
• Burned up
• Riled (up)
• -- up (agitated)
• Bugged or vexed