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Related Clues:
- Wear on one's conscience
- Bother big-time
- ___ Joe's
- "___ Joe's" (sandwich board message)
- Unmitigated ___
- Continuously bother
- Patronize, in a way
- Make anxious
- Really rankle
- Words on a sandwich board
- Brass nedk or bile
- Spleen or brass neck
- Bitterness of feeling or bodily bladder
- A sore spot or a bodily bladder
- This bladder is attached to the liver and stores bile