Related Clues:

• Vex a lot
• Bother greatly
• Bother continuously
• Trouble no end
• Irk to no end
• Bother (5)
• Patronize, as a diner
• Vex no end
• Boldness to a fault
• It may be unmitigated
• Irritate psychologically
• Unmitigated stuff
• Frequent, as a diner
• Trouble greatly
• Chutzpah, in the extreme