Related Clues:
- Major apprehension
- Down state
- Existential discomfort
- Neurotic feeling
- Acute but unspecific anxiety
- See 56 Down
- Anxiety variety
- ___, Inc. (company that sells demotivational posters)
- 'The Scream' evocation
- Perennial teenage feeling
- Recurring Woody Allen theme
- Lose heart
- Not just jitters
- High anxiety
- Far-from-calm feeling