Related Clues:

• Feeling of loss
• True pain
• Deep sorrow
• Extreme suffering
• Deep sadness
• Serious suffering
• Therapist's concern
• Focus of a hospital center
• Tear inducer
• ''. . . and the __ of defeat''
• Reaction to personal loss
• Awful struggle
• Psychologist's concern
• Excruciating pain
• Physical injury