Related Clues:

• First mate on dry land?
• The Guardian has women going for a female first
• The day before a holiday
• The "E" in 46-Down
• "One more sleep" time
• The E in NYE
• 12/24, say
• The day before Lunar New Year, for one
• Adam and —
• The first biblical lady
• Heavies regularly protecting first lady
• Bevvies taken regularly the night before
• Name dropped by fair lady in garden
• Oddly envies the first lady
• She “took of the fruit thereof, and did eat”