Related Clues:

• Anxiety cause
• Existential discomfort
• Italicize, perhaps
• Put pressure on
• Neurotic feeling
• Fear facing
• Burnout cause
• Acute but unspecific anxiety
• More than misgivings
• See 56 Down
• Motivation for rubbing one's temples
• Italicize, say
• Make a point of
• Headache cause
• Anxiety variety