Related Clues:

• Most painful -- ergo relax
• Most affectionate female doesn't, however upset
• With their time coming to end, big shops may become most annoyed
• Most aggrieved sailor put up with others
• Most piqued
• Miffed to the max
• Most tender to the touch
• With the most aches
• Superlatively irritated
• Least apt to forgive
• Most in need of ice
• Most affected by a workout
• Most in need of a massage
• Most loving
• As a result, remainder will be most upset