Possible Clues:

• Bari's region
• Bari is the capital of this region in south-east Italy
• Section of climbing trail up Alps in Italy
• The heel of Italy’s “boot”
• The 'high heel' of Italy's 'boot'
• Heel of Italy's 'boot'
• Feel bad, having got out of bed with a twist in the region of the heel
• Region of Italy; I, Paula (anag.)
• Drivers coming across sheepdog in part of Italy