Possible Clues:

• Resident of small country governed by First Lady, out of bounds
• Genetic material going back to Gold Rush in the past divides the French and Spanish
• One girl carrying another across river in small country
• Resident of microstate with gold, scarpered!
• Latin name for the Song of Simeon
• European lands boundlessly managed locking up gold
• European in The Principality for November
• At least one of two fled from small country
• Spaniard's neighbor