Possible Clues:

• Divorcee in a 1980s sitcom
• Title role in a 1980s sitcom
• Divorcée Lowell in an '80s sitcom
• Sitcom oldie, 'Kate & --'
• Jane's 1980s sitcom role
• Hurler Reynolds of the 40's-50's Yankees
• DivorcГ©e Lowell in an '80s sitcom
• Kate's friend
• 'The Mosquito Coast' hero
• Reynolds who pitched two no-hitters