Possible Clues:

• 1959 post-apocalyptic classic
• Novel by Einstein found in glassworks, we hear
• Shute's setting for Hartley's The Shrimp and the Anemone?
• Where holidaymaker may sit down to read a novel
• "And '___' (nothing happens!) ..."
• Gregory Peck film of '59
• 1957 novel, and a hint to the ends of 17-, 27- and 45-Across and 11- and 34-Down
• Hamlet feels there is one that shapes our ends