Possible Clues:

• Apostle loses heart with one complaint or another
• Pestilential epidemic
• Outbreak of a deadly disease, or infestation of pest like locusts
• Epidemic beginning to peak - long debate not right
• Widespread, contagious and destructive disease
• Pester convict beginning to undertake exercise outside
• Infection spreading up a leg
• Harry would make capital with the other side
• Deadly pestilence
• Destructive, highly contagious disease