Possible Clues:

• N. American bison
• Bewilder
• Steer perhaps for Great Lakes port
• By the sound of it, buy, son, even if it's so beastly big
• It's some way off a bull — almost
• 'Bill for Mr. Cody by son, by the sound of it (7)'
• City of New York on the shores of Lake Erie
• US city south of Niagara Falls
• New York port on the St Lawrence Seaway
• Beef source