Possible Clues:

• City where JFK was assassinated
• American city where JFK was killed
• City in Texas - all sad (anag)
• 'Boy meets girl' is the set-up in this former TV series
• City in Texas where JFK was assassinated
• Everything can be found in the German city
• City where JF Kennedy was assassinated
• Texan commercial city
• Home of the Cowboys
• Cotton Bowl city