Possible Clues:

• Game's second leg upset old college
• Nobody else's business?
• The only outlet for this game?
• Sort of business college once attached to Doctor No
• Sole supplier has short time to take on pool renovation in New York
• Dr No with strange ploy for domination
• Second refusal by old college to provide game
• Game whose tokens have included the starts of 16-, 20-, 26-, 49- and 55-Across
• Go in the corner of this room, pal having nobody to play with
• Beginning to moan about old former college game