Possible Clues:

• Marks & Spenser talk about introducing new stores initially
• White shirt woes
• Marks way by road from Edinburgh to London, north to south
• Marks volunteers getting involved in crimes
• Spray 'n Wash targets
• Dry cleaners' targets
• Marks to remove
• Splotches
• Ink spots and wine splashes, for two
• Dry cleaner's concerns