Possible Clues:

• Not a drug that's done any wrong?
• An individual passing empty day, lacking inspiration
• Annoyed, being pain reliever
• Easing pain and distress - annoyed (anag)
• Equivalent of a wink, perhaps, eastern state backed, as inoffensive
• Dull, unlikely to cause an offence
• Annoyed with pain-relieving drug
• Annoyed, irritated and dull
• Undistinctive
• Dull, inoffensive