Possible Clues:

• Sick and tired of what's said to the photographers and director not getting on
• Remove dairy produce before getting exasperated
• Fed up, needing lift after seeing The Mousetrap?
• McBain enters Leicester High, fed up
• Maybe Lancashire don's opposite, frustrated
• Fed up with shed south of Derby, say
• Sort of food that gets party females fed up
• Fed up with dairy product then act very loudly
• Exasperated, disgusted or disgruntled
• Derby tip perhaps gets you fed up!