Possible Clues:

• Oprah, at times
• Woman in the picture
• Woman actor
• She's maybe recast by direction
• She has a role inserting key in a lock
• Streep or Close
• Outstanding vessel containing foremost of tough rowers -- Redgrave, say?
• Player, a lock, joining clubs
• Helen Hunt or Holly Hunter, e.g.
• Bill has long hair, as a Thespian