Possible Clues:

• One might call it E, but I call it a pest
• Of a colony member
• One in a home-wrecking crew?
• Ant-like insect which destroys timber
• That'll eat you out of house and home, call it what you will over the East
• CAll it E, and it'll eat you out of house and home
• Thus might 6 down get to tie this in a knot and eat you out of house and home
• Call it English for a bug!
• Destructive insect
• Sounds anti enough to eat you out of house and home