Possible Clues:

• Italian city, associated with St Francis
• City of central Italy
• Home of Francis
• How silly is the one from Italy?
• Town of an animal-friendly saint
• What a fool Francis is - or was - for one!
• Where by tradition an animal is given primary importance?
• Fool is standing in one Italian town
• Italian town of St. Francis
• Part of midnight mass is identified with St Francis