Possible Clues:

• Slattern
• Hussy
• "The Ethical ___," relationship guide with a reclamatory title
• He or she gives it up
• Floozy
• 'Jane, you ignorant ___'
• 'Jane, you ignorant ___' (old 'SNL' line)
• 'A woman with the morals of a man,' per the Urban Dictionary
• Promiscuous girl