Possible Clues:

• Leader of orchestra lovin' a toy instrument
• First of our chances at redemption is nigh — alas we blow it
• Instrument caught in blade, in accident initially
• Instrument from old estate, say, indicator not actually starting
• "The Legend of Zelda: __ of Time": video game
• Instrument put into car in a hurry
• Old music-maker on foot presumably in Australia
• Small wind instrument
• Tin whistle relative
• Nothing for the start of 25 across in a blower