| Lack of vitality |
ANEMIA |
| Laid up |
ILL |
| Like the cosmos |
VAST |
| Mortgage option, for short |
REFI |
| Mover and shaker |
DOER |
| Musical writer with Rodgers |
HART |
| Necessary |
NEEDFUL |
| Newbie |
TYRO |
| Off the mark |
ERRANT |
| Off-limits |
NOGO |
| One of the "Desperate Housewives" |
BREE |
| Osaka sash |
OBI |
| Out there, so to speak |
WEIRD |
| Pitching star |
ACE |
| Price tag info |
COST |
| Promotional link |
TIEIN |
| Pull together |
GATHER |
| Purport |
ALLEGE |
| Rhapsodic poem |
ODE |
| Rivals of the Crimson |
ELIS |
| See 45-Across |
TESTS |
| Sheer folly |
IDIOCY |
| Solo of sci-fi fantasy |
HAN |
| Spar verbally |
ARGUE |
| Steeped thing on a string |
TEABAG |
| Sums up |
TOTALS |
| Sword handle |
HILT |
| Tout's tabulation |
ODDS |
| TV's "Science Guy" |
NYE |
| Tycoon, informally |
FATCAT |
| Volt-ampere |
WATT |
| Volume II of Churchill's monumental "The Second World War" |
THEIRFINESTHOUR |
| Voting "no" |
ANTI |
| With 56-Down, optometric exams |
EYE |
| With a glossy finish |
ENAMELED |
| Yank's land |
USA |
| Zellweger of Hollywood |
RENEE |
| ___ soul (music genre) |
NEO |