| Like a calico |
PIED |
| Many Manolo Blahniks |
PUMPS |
| Marine growth rich in iodine |
KELP |
| Michael who directed 'The Deer Hunter' |
CIMINO |
| New York's Mount ___ Hospital |
SINAI |
| Optional ACT components |
ESSAYS |
| Part |
ROLE |
| Part 2 of the quip |
TOKLEPTOMANIACS |
| Part 3 of the quip |
BECAUSETHEYTAKE |
| Pen |
SLAMMER |
| Pet that likes to be petted |
LAPCAT |
| Product of a zymurgist |
ALE |
| Rake in |
EARN |
| Really rankles |
EATSAT |
| Sauce made with roux, milk and cheese |
MORNAY |
| See 39-Down |
ERIE |
| Setting for many old films |
TCM |
| Sierra ___ |
LEONE |
| Simpletons |
GEESE |
| Singer recognized as the 'King of YouTube' in 2012 |
PSY |
| Slow pacesetter |
SNAIL |
| Some like them hot |
DATES |
| Something talked about in a TED talk |
IDEA |
| Sorry about |
RUING |
| Start of a quip about wordplay |
YOUCANTTELLPUNS |
| Tagamet competitor |
ZANTAC |
| Take a chance |
RISKIT |
| Tessellating artist |
ESCHER |
| Thumbs-down responses |
NOS |
| Thumbs-up response |
YES |
| Title with an apostrophe in the middle |
MAAM |
| Trip cause |
LSD |
| Way-out challenge? |
MAZE |
| With 48-Down, setting for Toledo |
LAKE |
| X setting, maybe |
MAP |
| ___ school |
MED |
| ___ tide |
NEAP |
